Hyperinsulinemia, Hyperglycemia, and Impaired Hemostasis
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چکیده
منابع مشابه
QTc dispersion, hyperglycemia, and hyperinsulinemia.
and Hyperinsulinemia To the Editor: QTc dispersion is an important predictor of cardiac mortality. In the Rotterdam Study,1 persons in the highest tertile (.60 ms) relative to the lowest tertile (,39 ms) of QTc dispersion had a 2-fold risk of cardiac death. The Rotterdam Study also confirms that QTc dispersion is larger in diabetic than in nondiabetic persons. QTc duration and QTc dispersion ar...
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Recent clinical studies demonstrated that transient postprandial hyperglycemia and hyperinsulinemia may contribute to the development of hypertension. Therefore, we investigated influence of acute hyperglycemia and/or hyperinsulinemia induced by glucose or insulin infusion on neuronal and humoral control of vascular tone in rats. Euglycemic male Wistar rats were pithed under anesthesia and arte...
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Type 2 diabetes and insulin resistance syndromes are associated with an increased risk for cardiovascular and thrombotic complications. A disturbed balance between coagulation and fibrinolysis has been implicated in the pathogenesis hereof. To determine the selective effects of hyperglycemia and hyperinsulinemia on coagulation and fibrinolysis, six healthy humans were studied on four occasions ...
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Impaired Hemostasis To the Editor: There is mounting evidence that severely impaired hemostasis is associated with a decreased risk of ischemic cardiovascular disease. In a study with long follow-up, hemophilic patients had an 80% reduction in the risk of fatal ischemic heart disease.1 In clinical practice, occurrence of cardiovascular disease is uncommon in patients with type 3 severe von Will...
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ژورنال
عنوان ژورنال: JAMA
سال: 2000
ISSN: 0098-7484
DOI: 10.1001/jama.283.2.221